Author Archives: GG


TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress. Florent Dufour, Thibault Rattier, Andrei Alexandru Constantinescu, Luciana Zischler, Aymeric Morlé, Hazem Ben Mabrouk, Etienne Humblin, Guillaume Jacquemin, Eva Szegezdi, Fabien Delacote, … Continue reading


Native ESI Mass Spectrometry Can Help to Avoid Wrong Interpretations from Isothermal Titration Calorimetry in Difficult Situations. Philippe Wolff, Cyrielle Da Veiga, Eric Ennifar, Guillaume Bec, Gilles Guichard, Dominique Burnouf, Philippe Dumas. J. Am. Soc. Mass Spectrom. 2017, 28, 347-357. link

Anion Recognition by Aliphatic Helical Oligoureas

Our latest publication on anion recognition by helical oligoureas has been published and highlighted on the cover of Chemistry a European Journal.


Anion Recognition by Aliphatic Helical Oligoureas. Vincent Diemer, Lucile Fischer, Brice Kauffmann, and Gilles Guichard. Chem. Eur. J. 2016, 22, 15684-15692. link  


Proteolytically Stable Foldamer Mimics of Host-Defense Peptides with Protective Activities in a Murine Model of Bacterial Infection. Emilie Teyssières, Jean-Philippe Corre, Stéphanie Antunes, Catherine Rougeot, Christophe Dugave, Grégory Jouvion, Paul Claudon, Guillain Mikaty, Céline Douat, Pierre L. Goossens, and Gilles … Continue reading


Anatomy of an Oligourea Six-Helix Bundle. Caterina M. Lombardo, Gavin W. Collie, Karolina Pulka-Ziach, Frederic Rosu, Valerie Gabelica, Cameron D. Mackereth, and Gilles Guichard. J. Am. Chem. Soc. 2016, 138, 10522-10530. link


N-Heterocyclic Carbene–Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy. Neila Chekkat, Georges Dahm, Edith Chardon, May Wantz, Justine Sitz, Marion Decossas, Olivier Lambert, Benoit Frisch, Riccardo Rubbiani, Gilles Gasser, Gilles Guichard, Sylvie Fournel, and Stéphane Bellemin-Laponnaz. … Continue reading


The meso Helix: Symmetry and Symmetry-Breaking in Dynamic Oligourea Foldamers with Reversible Hydrogen-Bond Polarity. Romina Wechsel, James Raftery, Dominique Cavagnat, Gilles Guichard, and Jonathan Clayden. Angew. Chem. Int. Ed. 2016, 55, 9657-9661. link


Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels. Julien Beyrath, Neila Chekkat, Cristian R. Smulski, Caterina M. Lombardo, Marie-Charlotte Lechner, Cendrine Seguin, Marion Decossas, Maria Vittoria Spanedda, Benoît Frisch, Gilles Guichard and Sylvie … Continue reading


Solid-Phase Synthesis of Hybrid Urea Oligomers Containing Conservative Thiourea Mutations. Stéphanie Antunes, Céline Douat and Gilles Guichard. Eur. J. Org. Chem. 2016, 12, 2131-2138. link