We are a research group dedicated to peptidomimetic chemistry

Welcome to the

Guichard Lab

Based in Bordeaux, our group’s research focuses on the biomimetic chemistry of peptides and proteins.


We are interested in designing and elaborating systems with protein like structure and functions and to investigate and develop their biological and biomedical applications.


Although centered on chemical synthesis, our research program is based on a multidisciplinary approach involving spectroscopic studies, crystallographic analyses, combinatorial techniques, binding studies.

Our latest


  • Last week, Gilles was awarded the DCO advanced researcher award for his career and contribution in foldamer chemistry and molecular recognition....

  • Our chapter entitled Urea based foldamers has just been released in the Reference work Methods in Enzymology. 50 days’ free access by clicking on this link before July 24, 2021 !...

  • See our last paper in Science Advances showing how a foldamer backbone can adapt to recognize a specific protein surface....

Discover our