Foldamer Chemistry

Our research in

Foldamer chemistry

SYNTHESIS OF FOLDED AND SELF-ASSEMBLED ARCHITECTURES MIMICKING PROTEINS

 

De novo design of synthetic objects with well-defined tertiary and quaternary structures mimicking functions of biomacromolecules represents an ultimate goal in biomimetic chemistry.

 

The design of discrete biotic and abiotic oligomers (i.e. foldamers) with predictable and well-characterized folding patterns (e.g. secondary structure stabilized by remote intrastrand interactions, local conformational control or solvophobic effects) has attracted considerable attention over the last twenty years.

Figure : Formation of columnar stacks by axial packing of H-bonded dimers of hybrid urea / amide macrocycles and close-ups of the interfaces between duplexes.

2017-2021

Sample Project

John Doe, Jane Doe, John Doe

 

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Figure : Formation of columnar stacks by axial packing of H-bonded dimers of hybrid urea / amide macrocycles and close-ups of the interfaces between duplexes.

2017-2021

Sample Project

John Doe, Jane Doe, John Doe

 

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Funded by :
Partners :

Figure : Formation of columnar stacks by axial packing of H-bonded dimers of hybrid urea / amide macrocycles and close-ups of the interfaces between duplexes.

2017-2021

Sample Project

John Doe, Jane Doe, John Doe

 

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Funded by :
Partners :

Figure : Formation of columnar stacks by axial packing of H-bonded dimers of hybrid urea / amide macrocycles and close-ups of the interfaces between duplexes.

2017-2021

Sample Project

John Doe, Jane Doe, John Doe

 

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Funded by :
Partners :