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Synthesis and structural characterization of alkyne-functionalized N-heterocyclic carbene complexes of ruthenium, palladium and rhodium.

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Helical Oligourea Foldamers as Powerful Hydrogen Bonding Catalysts for Enantioselective C-C Bond-Forming Reactions.

Bécart D, Diemer V, Salaün A, Oiarbide M, Nelli YR, Kauffmann B, Fischer L, Palomo C, Guichard G.

J. Am. Chem. Soc. 2017, 139 (36), 12524-12532. link

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Foldamers in Medicinal Chemistry.

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Effect of replacing main-chain ureas with thiourea and guanidinium surrogates on the bactericidal activity of membrane active oligourea foldamers.

Antunes S, Corre JP, Mikaty G, Douat C, Goossens PL, Guichard G.

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Proline-rich antimicrobial peptides targeting protein synthesis.

Nat. Prod. Rep. 2017, doi: 10.1039/c7np00020k. link

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Molecular Recognition within the Cavity of a Foldamer Helix Bundle: Encapsulation of Primary Alcohols in Aqueous Conditions.

Gavin W. Collie, Remy Bailly, Karolina Pulka-Ziach, Caterina M. Lombardo, Laura Mauran, Nada Taib-Maamar, Jean Dessolin, Cameron D. Mackereth, and Gilles Guichard.

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N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death.

Florent Dufour, Thibault Rattier, Sarah Shirley, Gaelle Picarda, Andrei Alexandru Constantinescu, Aymeric Morlé, Al Batoul Zakaria, Guillaume Marcion, Sebastien Causse, Eva Szegezdi, Dirk Michael Zajonc, Renaud Seigneuric, Gilles Guichard, Tijani Gharbi, Fabien Picaud, Guillaume Herlem, Carmen Garrido, Pascal Schneider, Chris Alan Benedict, and Olivier Micheau.

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Hetero-oligomerization between the TNF receptor superfamily members CD40, Fas and TRAILR2 modulate CD40 signalling.

Cristian R Smulski, Marion Decossas, Neila Chekkat, Julien Beyrath, Laure Willen, Gilles Guichard, Raquel Lorenzetti, Marta Rizzi, Hermann Eibel, Pascal Schneider and Sylvie Fournel.

Cell Death and Disease 2017, 8, e2601; doi:10.1038/cddis.2017.22 link

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TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress.

Florent Dufour, Thibault Rattier, Andrei Alexandru Constantinescu, Luciana Zischler, Aymeric Morlé, Hazem Ben Mabrouk, Etienne Humblin, Guillaume Jacquemin, Eva Szegezdi, Fabien Delacote, Naziha Marrakchi, Gilles Guichard, Catherine Pellat-Deceunynck, Pierre Vacher, Patrick Legembre, Carmen Garrido, Olivier Micheau.

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Native ESI Mass Spectrometry Can Help to Avoid Wrong Interpretations from Isothermal Titration Calorimetry in Difficult Situations.

Philippe Wolff, Cyrielle Da Veiga, Eric Ennifar, Guillaume Bec, Gilles Guichard, Dominique Burnouf, Philippe Dumas.

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