02 Apr New publication
See our last paper in Science Advances showing how a foldamer backbone can adapt to recognize a specific protein surface....
30 Mar Useful “Fake” Peptides
Oligourea foldamers mimic peptides’ alpha-helices and effectively bind to drug targets. Our latest publication on « Structure-guided design of peptide-oligourea hybrids as inhibitors of protein-protein interactions and structural insights into protein surface recognition by oligourea foldamers» has been highlighted by the Editors of ACIE as Hot...
19 Jul Our Chapter in the book Comprehensive Supramolecular Chemistry II
Our chapter entitled Foldamers in Medicinal Chemistry has just been released in the Reference work Comprehensive Supramolecular Chemistry II....
31 May Molecular Recognition within the Cavity of a Foldamer Helix Bundle
Our latest publication on molecular recognition within the cavity of a foldamer helix bundle has been published and highlighted on the cover of the Journal of the American Chemical Society. About the Cover: Towards the development of functional water-soluble foldamers, we report here the first example of self-assembled foldamers able to recognize...